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doi: 10.1128/CMR.00047-19 43 CaoX.-L.ShenH.XuY.-Y.XuX.-J.ZhangZ.-F.ChengL.et al

[30] [34] [35] [36] [37] Production and consumption of oxidants [edit] One source of reactive oxygen under normal conditions in humans is the leakage of activated oxygen from mitochondria during oxidative phosphorylation

Studies on gene knockout mice have demonstrated that deletion of the 5 nAChR subunit significantly reduces nicotines aversive effects, enabling animals to tolerate higher doses of nicotine ( 5 subunit