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The study by Honda et al., conducted in 2017, was an open-label, single-arm, multicentre pilot study that evaluated the therapeutic effect of oral glutathione administration (300 mg/day) in patients with NAFLD through the evolution of biochemical indices (ALT) and liver fat levels assessed by VCTE (79)

doi: 10.1016/j.aquaculture.2020.735944 152 LiuYYuMCuiJDuYTengXZhangZ

Villafuerte G, Miguel-Puga A, Murillo Rodrguez E, et al

OCLC 299710911

Even though developing a vaccine against GPNMB positive cells seems to be beneficial, the challenge remains to only deplete cells with the highest expression of the protein but not the cells expressing it at a physiological level 63