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demonstrated that the co-administration of Diane-35 and metformin resulted in decreased androgen receptor expression, increased GLUT4 expression, and modulation of cellular autophagy initiation by inhibiting IGF-1, ultimately leading to the suppression of EC development mediated by the mTORC pathway (Liu Y

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By tempering the activation and infiltration of these immune cells into the inflamed colonic tissue, Rutin contributes to a controlled and measured immune response

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