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Res Sq2024 Sep 24

J ., 23 (4), 629636

84 In the elderly population, several distinct sleep-related changes can be detected via EEG: diminished sleep continuity, shortened REM sleep latency, reduced SWS, and increased nighttime awakenings

It suggests that ozone may exert its therapeutic effects through modulation of the Nrf2 and HIF-1 pathways, potentially mitigating oxidative stress injury and demonstrating possible protective effects against ischemia-hypoxia conditions