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[11] TMG can help replenish methyl groups and facilitate the clearance of nicotinamide, theoretically reducing the buildup of by-products that could cause fatigue or headaches in some individuals

The TB-500 protocol is one of the tools we use to address those injuries at the biological level rather than managing symptoms while the clock runs out

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I published a patient information sheet on it (just before I created my website), and several of my patients tried it with modest effects