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6 Feature Importance for Biological Aging (FIBA) to derive a cognition-associated brain aging model

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The sustained tonic GH/IGF-1 elevation it produces rather than pulsatile bursts is both a research advantage (easier to measure steady-state changes in body composition) and a design consideration (it does not replicate physiological GH pulsatility, which may matter in neuroendocrine studies)

Rights and permissions About this article Cite this article Arnett, M., Muglia, L., Laryea, G

Ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis and an oncogenic c-MYC transcriptional target (Bello-Fernandez et al., Figure 1)