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A recent meta-analysis found treatment with metformin to be significantly associated with an increased incidence of vitamin B12 deficiency and reduced serum levels.8 It is therefore possible that the etiology in this case may have been twofold

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Many patients report feeling more alert and focused shortly after starting treatment

Vegans and Vegetarians People following plant-based diets may have lower Vitamin B12 intake and may benefit from discussing B12 support with a provider

It helps reduce food cravings and increase feelings of fullness, thus helping you stick to your low-calorie diets and lose weight more effectively