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doi:10.4103/0974-7753.100090 99 Taylor, M

They additionally represent genotoxic stress capable of DNA adduct formation, thereby promoting the earliest stages of carcinogenesis

FI, which depends on the environment of these aromatic residues, reflects tertiary structural alterations in the protein at different pH conditions (Wang et al., 2017)

Sarnak MJ, Levey AS, Schoolwerth AC, Coresh J, Culleton B, Hamm LL, et al

On the other hand, ANG II signaling via angiotensin II type 1 receptors (AT-1Rs) disrupts both efferocytosis and ECs function as this peptide shifts macrophages from the phagocytic (M2) to proinflammatory (M1) phenotype, a pattern consistent with autoimmune inflammation (Belline et al., 2011)