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Ventura M, Melo M, Carrilho F

Among these elements, ATF3 predominantly regulates the basal and stress-induced expression of ChaC1 through ATF/CRE, while ATF4 primarily regulates stress-induced ChaC1 expression through ATF/CRE and ACM (48)

Perturbations and disturbances to the ER environment can result in the accumulation of unfolded and misfolded proteins within the ER, leading to disruption of protein homeostasis, a condition known as ER stress

The addition of GIP receptor activity may actually reduce GLP-1 related gastrointestinal discomfort rather than adding to it

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