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Depression patients with hypothyroidism are at increased risk of depression, but in the elderly patient, sometimes a severe psychosis may develop often shortly after commencing treatment

Leonetti, OpenCell: Endogenous tagging for the cartography of human cellular organization

Therefore, catalysis can only be supported by homooligomers and various oligomeric states can support the required active site architecture (Figure 1)

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The dosage is highly variable and determined solely by the treating physician based on diagnosis (e.g., severity of deficiency, presence of neuropathy)