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While the highest expression levels were consistently observed in the brain, NRN1 transcripts were also detected at moderate levels in skeletal muscle, lung, thymus, pancreas, placenta, liver, and heart

And there are some tests that are, especially for young children, there are things to be ruled out neurologically, like sub-clinical seizures, electrical status epilepticus of sleep, and so it's a process

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preclinical studies utilizing cell culture and animal models