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Proc Natl Acad Sci USA (2019) 116:987782

Studies have examined retatrutide in the context of GLP 1, GIP, and glucagon receptor signaling, primarily in preclinical and clinical research settings

Reference MK-677 Dosing Protocol MK-677 studies have applied the compound in doses of up to 25mg/daily for up to two years, while considerably shorter studies have also administered 50mg/daily [16, 20]