LAST UPDATED 2026-05-19
In MASLD, SIRT1 acts as a substrate of E3 ligases, undergoing K48-linked ubiquitination and degradation, which exacerbates hepatic steatosis 41
AOD-9604: Metabolic enhancer AOD-9604 is a modified fragment derived from the C-terminal (176-191) portion of human growth hormone (HGH) that works directly on the fat cells without affecting muscle growth and blood sugar levels
PLoS ONE 9:e89202
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