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Between 10% and 20% of PNH patients experience clinically significant loss of red blood cells outside of the blood vessels, a condition known as extravascular haemolysis, and continued anemia symptoms when on C5 inhibitors

Currently it is unknown under what conditions (if any) it is safe to use MOTS-c because there are no completed clinical trials

Here are a few examples: Athlete Recovery: Local athletes have reported significantly reduced recovery times and enhanced muscle strength after using BPC-157

Arch Intern Med 163: 286292, 2003

Therefore the development of a two-in-one vaccine that could elicit protection against both these infections is a subject of great interest