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Abbreviations 4-OH-E 1 : 4-Hydroxyestrone BAZ: Bazedoxifene BSO: l-Buthionine-( S,R )-sulfoximine cPTIO: 2-(42 Carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide CPZ: Chlorpromazine DFO: Deferoxamine eNOS: Endothelial nitric oxide synthase ERO1: ER oxidoreductin 1 Fer-1: Ferrostatin-1 GPX4: Glutathione peroxidase 4 GSH: Glutathione iNOS: Inducible nitric oxide synthase NAC: n-Acetyl-l-cysteine Nec-1: Necrostatin-1 nNOS: Neuronal nitric oxide synthase NO: Nitric oxide NOS: Nitric oxide synthase PDI: Protein disulfide isomerase ROS: Reactive oxygen species SMT: S -Methylisothiourea sulfate SNP: Sodium nitroprusside Trolox: 6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid TrxR1: Thioredoxin reductase 1 References Sun Y, et al