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Characterization and proteome of circulating extracellular vesicles as potential biomarkers for NASH

Taken together, these data demonstrate that mitochondrial function is intrinsically linked to 5FU sensitivity, and that its inhibition may provide an opportunity to increase 5FU efficacy

39: 19325 Marquez A, Todd M

Human primary hepatocyte culture Human primary Upcyte hepatocytes were cultivated in medium containing high concentrations of glucose (25 mM) and palmitate (100 nM) for 5 days in the presence or absence of TLC-2716, and intracellular lipids were measured by Bodipy staining

Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein