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As our manuscript was being prepared, two laboratories have reported anti-ferroptotic functions of cholesterol in different cells

An increase in the activity of plasma membrane H + -ATPase and a decrease in the activity of plasma membrane Na + /H + antiporter, respectively, can explain the observed increase in the absorption of K + and Ca 2+ ions and the decrease in the buildup of harmful Na + ions

Together, they: Enhance mitochondrial efficiency , ensuring that the body uses fat stores for energy

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