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Research is ongoing to expand the range of treatment options and studies have been undertaken to evaluate the use of vitamins (e.g., vitamin E, vitamin B6) and/or supplements (e.g., melatonin, branched chain amino acids) to help manage TD

In addition, changes in the microbiome diversity were associated with alterations in bile acid synthesis secondary to LT and the choice of different immunosuppressive agents two years after LT

The samples were incubated at room temperature (25 C) on a shaker (100 rpm) for 24 h

Robles-Rengel R, Florencio FJ, Muro-Pastor MI

A study conducted on the HCT-8 colorectal cell line demonstrated that curcumin increases the sensitivity of 5-FU for the colorectal cell line by downregulating the expression of P-GP and HSP-27, both of which are associated with multidrug-resistant (MDR) proteins [151]