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Cell lysate was sonicated and centrifuged at 14,000 rpm at 4 C to remove cell debris

Circ-ITCH could protect renal function by targeting miR-214-3p, promoting the expression of ABCA1, and inhibiting oxidative stress and mitochondrial damage[26]

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A originates from proteolytic cleavage of the transmembrane amyloid precursor protein (APP), whereas NFTs consist of hyperphosphorylated and misfolded tau proteins (Ballard et al., 2011)