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As absorption is reduced, body stores become low and a deficiency occurs Underlying diseases most commonly include: IBD (inflammatory bowel disease) Intestinal cancer (especially small cell lymphoma) Liver disease Pancreatitis and other pancreatic diseases Symptoms of low B12 levels Typically found in middle-aged or older cats that present with: Weight loss Diarrhea Vomiting Anorexia Thickened intestines In humans, B12 deficiency may also be associated with dementia, cardiovascular disease, and a certain type of anemia, although these are not specifically recognized problems in cats

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[27] documented increased levels of estradiol, LH, and FSH following both PRP and PRF treatment, Kutluhan et al

98,99 However, it has been reported that the dephosphorylation of NMN into NR by extracellular 5-nucleotidases is required for the uptake and utilization of NMN in cellular NAD + synthesis

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