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Dosing begins low and gradually increases over the course of several weeks, allowing the body to adjust and reducing the intensity of gastrointestinal side effects during the initial phase

Included in the situations which may make dosage adjustments necessary are changes in clinical status secondary to remissions or exacerbations in the disease process, the patients individual drug responsiveness and the effect of patient exposure to stressful situations not directly related to the disease entity under treatment

It helps shift melanin synthesis toward lighter pigments, resulting in a more even skin tone over time

One should avoid sun exposure, the use of other hair removal techniques, scratching and picking and should apply the prescribed cream to avoid adverse effects and increase the chances for better and extended results

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