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performed a metabolism study with bromfenac to scrutinize the formation of reactive intermediates and their linkage to the hepatotoxicity of this compound ( In vitro studies have revealed that bromfenac requires conjugation by UGTs to form a bromfenac glucuronide intermediate that cyclizes to a major metabolite, bromfenac indolinone (BI)

Determination of the total antioxidant activity in fruits by the capture of free radical DPPH

A Phase I study was registered to test the safety and pharmacokinetics of oral BPC-157 tablets in 42 healthy volunteers

Mechanistic investigations of the mitochondrial complex I inhibitor rotenone in the context of Pharmacological and safety evaluation

This is consistent with our observation that persister cells have downregulated expression of glutathione and NADPH biosynthesis genes (Extended Data Table 2)