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Fagone E, Conte E, Gili E, Fruciano M, Pistorio MP, Lo Furno D et al (2011) Resveratrol inhibits transforming growth factor--induced proliferation and differentiation of ex vivo human lung fibroblasts into myofibroblasts through ERK/Akt inhibition and PTEN restoration

J Pineal Res (2016) 60(3):31326

In the early inflammatory phase of healing, older individuals exhibit diminished capacity to control reactive oxygen species (ROS) and to mount robust immune cell responses [87]

Results vary based on baseline NAD+ status, age, and overall health

As expected, the remodeled bioenergetics and the oxidant environment reduced cardiac function and decreased life expectancy