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[11] [12] The combination might theoretically offer complementary cardiovascular support, but robust evidence is lacking, and neither is included in UK clinical guidelines for cardiovascular disease management or lipid modification

Feddock J, Kudrimoti M, Randall M

2007 Aug;114(8):1028-30

Genes such as calpain 2 ( CAPN2 ), collagen type I alpha 1 chain ( COL1A1 ), collagen type I alpha 2 chain ( COL1A2 ), collagen type VI alpha 1 chain ( COL6A1 ), collagen type VI alpha 2 chain ( COL6A2 ), and collagen type VI alpha 3 chain ( COL6A3 ) were identified as key genes [41]