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If immunotherapy aims to establish protective immune memory comparable to that induced by acute infection, then its failure to do socoupled with the insufficient tumor-killing capacity that permits on-treatment progressionreveals fundamental limitations in current strategies and underscores the need for a mechanistic explanation

Briefly, PBS-flushed and longitudinally cut intestinal pieces were vortexed in ice cold PBS for 5 min, transferred to 30 mM EDTA, and vortexed for 5 min

Henmi H, Endo T, Kitajima Y, Manase K, Hata H, Kudo R