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A preclinical study of the effects of seabuckthorn (Hippophae rhamnoides L.) leaf extract on cutaneous wound healing in albino rats

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CKD - defined as kidney damage or a glomerular filtration rate below 60 mL/min/1.73 m 2 for three or more months - is an independent risk factor for the development of CVD, including atherosclerosis, with CKD patients displaying a higher prevalence and progression of atherosclerotic lesions (Valdivielso et al., 2019

Here the THF, formed above is converted to the folate derivative 5,10-methylene-THF by the enzyme serine hydroxymethyl transferase (SHMT)

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