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ROIs reactive oxygen intermediates Glucocorticoids on binding to the glucocorticoid receptor (GR), promote the dissociation of heat shock proteins (HSPs), and the ligand-receptor complex translocates to the nucleus then binds to palindromic DNA sequences, called glucocorticoid response elements (GREs)

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Targeted therapy Targeted therapy predominantly depends on advancements in tumor molecular biology and genomics to address specific molecules or signaling pathways that are integral to tumor initiation and progression

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Following this, the gel was rinsed twice with deionized water and incubated with 0.01% of l-DOPA at 37 C for 4 h for the development of dark-brown color bands by the enzymatic activity of the mh-Tyr