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doi:10.1210/clinem/dgaa798

However: Avoid stacking MK-677 with injectable secretagogues this is usually redundant and may increase side effects

Physicians typically evaluate body composition changes, any side effects, and metabolic markers before continuing or adjusting protocols

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Standard Therapeutic Cycle (12 Weeks): Clinical trials frequently employed 12-week protocols, which provide sufficient duration for measurable metabolic changes while establishing safety through comprehensive monitoring