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Data from recent studies, in particular LEROS, provide a more accurate picture of the efficacy of idebenone in a subset of patients with LHON, in particular those with chronic LHON between 1 and 5 years disease duration

Triple mechanism: matrix + vessels + cells

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Following euthanasia, liver, heart, and pancreas tissues were rapidly excised and fixed in buffered formalin-saline for subsequent histopathological and immunohistochemical analyses

That was just the start of Johnson's migraines