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139 In addition to regulating fatty acid metabolism, PGC1 is a master regulator of mitochondrial biogenesis and energy metabolism

doi: 10.1158/0008-5472.Can-15-1545 [DOI] [PubMed] [Google Scholar] 112

MACROPHAGE SCAVENGER RECEPTOR (SR-AI) In 1979, Brown and Goldstein demonstrated that macrophages had specific binding sites for acetylated LDL (AcLDL) that allowed uptake of this modified LDL even in the presence of high cellular cholesterol levels (298)

These results suggested a state of high oxidative stress in the interior of the herniated nucleus pulposus, which likely accelerates disc degeneration

We found NAC or GSH promoted colony formation in MHCC-97L cells and HepG2 cells (Additional file 1: Fig