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Silibinin, the main active ingredient isolated from Silybum marianum (L.) , has been reported to administrate dramatically inhibited KA-induced GCD and mTORC1 activation, while the phosphorylation levels of the mTORC1 substrate 4E-BP1 and p70S6K were also altered ( Terpenoids can also play a therapeutic role through other mechanisms

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10.1016/j.tig.2022.08.005 Trends Genet

Clinical and preclinical programs span a broad range, with notable success stories emphasizing the effectiveness of VLPs

Li Y, Tan Z, Li Z, Sun Z, Duan S, Li W (2012) Impaired long-term potentiation and long-term memory deficits in xCT-deficient sut mice,