Fluid and electrolyte disturbances: Sodium retention Fluid retention Congestive heart failure in susceptible patients Potassium loss Hypokalemic alkalosis Hypertension Musculoskeletal: Muscle weakness Steroid myopathy Loss of muscle mass Osteoporosis Vertebral compression fractures Aseptic necrosis of femoral and humeral heads Pathologic fracture of long bones Gastrointestinal: Peptic ulcer with possible subsequent perforation and hemorrhage Pancreatitis Abdominal distention Ulcerative esophagitis Dermatological: Impaired wound healing Thin fragile skin Facial erythema Increased sweating May suppress reactions to skin tests Petechiae and ecchymoses Neurological: Convulsions Increased intracranial pressure with papilledema (pseudotumor cerebri) usually after treatment Vertigo Headache Ophthalmic: Posterior subcapsular cataracts Increased intraocular pressure Glaucoma Endocrine: Menstrual irregularities Development of cushingoid state Suppression of growth in children Secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery, or illness Decreased carbohydrate tolerance Manifestations of latent diabetes mellitus Increased requirements for insulin or oral hypoglycemic agents in diabetics Metabolic: Negative nitrogen balance due to protein catabolism Miscellaneous: Hyperpigmentation or hypopigmentation Subcutaneous and cutaneous atrophy Sterile abscess Postinjection flare, following intra-articular use Charcot-like arthropathy Itching, burning, tingling in the ano-genital region A
J Neurosci Res (2018) 96(6):92750
We next assessed whether OxPhos signalling (as an indicator of mitochondrial metabolism) alone was sufficient to predict response to 5FU-based chemotherapy
Dihexa is a neuro-focused peptide that appears to strengthen communication between brain cells, supporting memory, learning, and mental processing speed, which can make stressful days feel more manageable
Macromol Mater Eng 286(9):560563 Monte LG, Santi-Gadelha T, Reis LB, Braganhol E, Prietsch RF, Dellagostin OA, Lacerda ERR, Gadelha CAA, Conceio FR, Pinto LS (2013) Lectin of Abelmoschus esculentus (okra) promotes selective antitumor effects in human breast cancer cells
