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Description

Exosome for mRNA delivery: strategies and therapeutic applications

doi: 10.1073/pnas.0711566105

10.1155/2023/8871299 86 KhatunS.ChatterjeeS.ChattopadhyayS

Enhanced immune response by HOTTIP-induced polarization of local and circulating macrophages to the M1 phenotype also positioned macrophage-derived lncRNAs like HOTTIP as interesting candidates for individualized cancer immunotherapy ( Recent studies indicate that the best application of macrophage-derived lncRNAs to personalized oncology is through integration of immune and molecular signatures, but not as individual markers