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Acknowledgments The authors acknowledges the use of Biorender that is used to create the figure

A review of the literature provides substantial evidence suggesting that AA is a tissue-specific immunological disorder

In the past 10 years, ferroptosis, an iron-dependent form of regulated cell death, has become increasingly recognized as an important process that mediates the pathogenesis and progression of numerous cardiovascular diseases, including atherosclerosis, drug-induced heart failure, myocardial ischaemiareperfusion injury, sepsis-induced cardiomyopathy, arrhythmia and diabetic cardiomyopathy

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