glutathione persister cell

glutathione persister cell Drug-tolerant cancer cells are vulnerable to GPX4 inhibition Persister cancer cells: Iron addiction

Name: glutathione persister cell Drug-tolerant cancer cells are vulnerable to GPX4 inhibition Persister cancer cells: Iron addiction
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Persister cancer cells: Iron addiction and vulnerability to ferroptosis: Molecular Cell Low GPX4 drives a sustained drug tolerant persister state in TNBC by a targetable adaptive FSP1 upregulation ScienceDirect Real Time Monitoring of Glutathione in Living Cells Reveals that High Glutathione Levels Are Required to Maintain Stem Cell Function: Stem Cell Reports Glutathione accelerates the cell cycle and cellular reprogramming in plant regeneration: Developmental Cell Mechanism of Drug Tolerant Persister Cancer Cells: The Landscape and Clinical Implication for Therapy Journal of Thoracic Oncology

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showed that MitoVitE, -tocopherol, and Trolox all reduced oxidative stress, NFB activation, and cytokine release in endothelial cells under sepsis-like conditions

Below, we summarize novel therapeutic targets and strategies with clinical application potential to provide more options for disease treatment (Table 1)