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10.1007/s10565-016-9363-8 12 BiX.HanL.QuT.MuY.GuanP.QuX.et al (2017)

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Metformins role in mitigating oxidative stress, a state of imbalance between the production of reactive oxygen species (ROSs) and the capacity of the cells antioxidant systems to neutralize them, is equally important

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Only the loci that exhibited statistically significant differences between the compared groups were chosen for further analysis

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When used in lower doses, such as those achievable by taking pills or using IV doses below 10-12 grams, vitamin C acts as an antioxidant

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