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Albert GC, Cook CM, Prato FS, Thomas AW

The ecological imbalance of intestinal flora, alterations of intestinal cell permeability, liver injury, endoplasmic reticulum stress, abnormal activation of cellular signaling pathway, as well as dietary and genetic factors of patients, have all been implicated in the occurrence of NAFLD (Williams et al.,

This could be due to ga enetic disorder, inadequate intake, diarrhoea, liver or kidney disease, and use of certain medications

Tetrahydrocurcumin, a major metabolite of curcumin, ameliorates allergic airway inflammation by attenuating Th2 response and suppressing the IL-4R-Jak1-STAT6 and Jagged1/Jagged2 -Notch1/Notch2 pathways in asthmatic mice