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The raised flap is entirely dependent on blood flow through small vessels at its base, and any factor that compromises oxygen delivery (anaemia being a major one) puts the flap at risk

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What Your Doctor Should Know Before Prescribing Either Drug Any prescriber considering phentermine or tirzepatide should obtain a detailed cardiovascular history, recent blood pressure readings, and an EKG if the patient has hypertension, prior arrhythmia, or family history of sudden cardiac death