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Figure 3 illustrates the interaction between peripheral inflammation, brain inflammation, and the HPA axis, highlighting their roles in stress-related disorders

In in vitro maturation (IVM) cultures, the addition of Necrostatin-1 significantly increased the expression of GDF9, Mad2, and Bcl-2 in immature oocytes in mice and prevented oxidative stress-mediated deterioration of oocyte quality (Tsui et al., 2017)

Wang, S., Ye, X., Sun, Y., Liang, J., Yue, P., & Gao, X

Obstructive sleep apnea (OSA) and pulmonary arterial hypertension (PAH) David Flenley coined the term Overlap Syndrome (OS) when he described Obstructive Sleep Apnea (OSA) in patients with COPD and showed that they had a higher risk of mortality and ECOPD 119

Liu N, Zhou KI, Parisien M, Dai Q, Diatchenko L, Pan T