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For example, when the proteasome is pharmacologically inactivated, ubiquitinylated proteins are identified by molecular adaptors that link aggregates/misfolded proteins to dynein motors, which in turn transport their cargo along microtubule tracks to deliver the aggregates to a juxtanuclear site called the aggresome 3,4,5

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Cloning of phospholipid hydroperoxide glutathione peroxidase (PHGPx) as an anti-apoptotic and growth promoting gene of Burkitt lymphoma cells