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Hassan and Aarts, 2011

MTHFR polymorphisms and Disease

These immune improvements aligned with the increases in glutathione levels in PBMCs (white blood cells)

2.2.3 Infections Due to their functional asplenia and functional immunocompromised status, patients with SCD are more vulnerable to infections with encapsulated organisms (increased bone marrow turnover and altered complement activation)

Figure 3 7 The contradiction of ferroptosis between radiation-induced injury and radiosensitivity 7.1 Ferroptosis serves as a balancing mechanism between radiosensitivity and radiation-induced injury As previously mentioned, using these drugs to induce ferroptosis in tumor cells can effectively kill cancer cells and enhance radiosensitivity, while inhibiting ferroptosis in normal cells helps protect tissues and organs, thereby reducing radiation damage