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CW: Software, Writing original draft, Writing review and editing

Denholm, L

The resolved and predicted structure are highly similar

After blocking with 5% nonfat dry milk in TBS-Tween for 12 h at room temperature, blots were incubated with appropriate primary antibodies overnight at 4 C

Consisting of dimeric transcription factors such as Jun and Fos, AP-1 binds to DNA motifs, such as TPA-responsive element (TRE) and cAMP-responsive element (CRE), initiating transcription of genes critical for cell survival and stress adaptation 73,74