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2004, Ed Masson, Barcelona Hvas AM, Juul S, Nexo E, Ellegaard J: Vitamin B-12 treatment has limited effect on health-related quality of life among individuals with elevated plasma methylmalonic acid: a randomized placebo-controlled study

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Third, it stimulates glucose-dependent insulin secretion from pancreatic beta cells while suppressing inappropriate glucagon release improving glycemic control without significant hypoglycemia risk