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Risks from Concomitant Use with Benzodiazepines or Other CNS Depressants]

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In terms of angiogenesis, lactate can enter vascular endothelial cells via MCT1, leading to IB phosphorylation and subsequent degradation, thereby activating the NF-B pathway and upregulating IL-8 transcription, a key mediator of angiogenesis

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CrossRef Gut microbiota dysbiosis in chronic liver disease: Mechanisms driving hepatocellular carcinoma progression and therapeutic implications of Chinese medicine Shihao Zheng, Fan-e Cheng, Xiaoke Li, Hongbo Du, Peng Zhang, Xiaobin Zao, Yongan Ye, Xinyue Shi Molecular Aspects of Medicine.2026