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Why is S-23 used in androgen receptor pharmacology research

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Quick Answer Neither compound is objectively "better." Available studies indicate MOTS-c is a naturally occurring mitochondrial-derived peptide that optimizes whole-body metabolic function and insulin sensitivity

For example: FDA communications indicate AOD-9604 was removed from Category 2 in 2024 because nominations were withdrawn, while also noting FDA would consult the Pharmacy Compounding Advisory Committee (PCAC) about potential inclusion on the 503A bulks list

The problem can be, however, that the digestive system isn't always efficient at absorbing the compound, meaning a large amount can simply pass straight through unabsorbed