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NADPH oxidase (NOX), lipoxygenase, cyclooxygenase (COX), xanthine oxidase (XO), uncoupled nitric oxide synthases (NOS), cytochrome P450, and mitochondrial respiration are the most common enzymatic causes of ROS in CVD [11]

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10.1002/mnfr.201500918 127

Pharmaceuticals and microplastics pose significant risks to water quality and aquatic life due to their bioactivity and toxic metabolites ( Ibuprofen is commonly detected in surface waters at concentrations ranging from ng/L to g/L