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Chang M C, Lin L D, Wu M T, et al

has shown that glycine regulates the levels of S-adenosylmethionine (a direct methyl donor), which promotes the methylation of the GPX4 promoter, thereby enhancing the ferroptosis of RA-FLS ( Galectin-1 derived peptide 3 (G1dP3), a bioactive peptide derived from the galectin-1 structural domain, has potent anti-inflammatory effects on RA-FLS ( Besides these ferroptosis inducers, a recent study has demonstrated that icariin inhibits ferroptosis by activating the Xc-/GPX4 axis, thereby protecting RA-FLS from LPS-induced cell death

Rho kinase inhibitor AMA0526 improves surgical outcome in a rabbit model of glaucoma filtration surgery

We have preliminary evidence indicating greater glutathionylation in Ames mice (Brown-Borg, unpublished data)

doi:10.1021/acsnano.1c08464 11