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These findings suggest that periodontitis aggravates diabetic pancreatic injury, at least partly through neutrophil activation

Nevertheless, several members of the Work Group felt that a short-term trial of L-carnitine was reasonable in selected patients with these symptoms who are unresponsive to other therapies, in light of its favorable side effect profile, lack of alternative effective therapies, and the findings from some studies of improvement in these symptoms with L-carnitine therapy

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These factors providing redundant angiogenic signals have also other roles in cancer and many approaches to target them are being investigated

The molecule is too large to cross the lining of the mouth without specialized formulation, and the only published study to test the question, in beagle dogs, found minimal absorption