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Although soto-p 8 was detectable only at 48 h and below the LOQ, soto-p 7 was detected as early as 2 h, peaking at 2448 h, consistent with the reported ~24 h turnover rate of KRAS G12C (Fig

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In mammals, the GPX family consists of eight members

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The pivotal studies, conducted under GLP, provided the foundational data that was later included in the investigational new-drug dossiers submitted to the Food and Drug Administration (FDA) and European Medical Agency (EMA)