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It is thought that endothelial function is a therapeutic target for atherosclerosis

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In this regard, it is interesting that IgG antibodies that show similar FcRn binding properties can have variable plasma half-lives due to differences in biophysical properties, such as pI and net charge, which affect cellular handling 83,84,85,86,87

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Hepatocyte growth factor-activated NF-B regulates HIF-1 activity and ODC expression, implicated in survival, differently in different carcinoma cell lines